| Autor: |
Chee, Y. L., Culligan, D. J., Olson, J. A., Molyneaux, P., Kurtz, J. B., Watson, H. G. |
| Předmět: |
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| Zdroj: |
British Journal of Haematology; Sep2000, Vol. 110 Issue 4, p874-875, 2p |
| Abstrakt: |
Varicella zoster virus (VZV) infection involving the posterior segment of the eye after fludarabine treatment has not previously been described. Two patients, who had completed fludarabine treatment 3 and 18 months previously, presented with visual loss that had been preceded by a recent history of cutaneous zoster. The use of the polymerase chain reaction (PCR) for VZV DNA from ocular specimens allowed rapid confirmation of clinical diagnosis and treatment with a good outcome in one patient. With the increasing use of fludarabine and other purine analogues, an awareness of such complications is important because of their potentially sight-threatening consequences. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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