Comparison of rufloxacin and norfloxacin effects on faecal flora.

Autor: Marco, F., Giménez, M. J., de Anta, M. T. Jimenez, Marcos, M. A., Salvá, P., Aguilar, L., Jiménez de Anta, M T
Zdroj: Journal of Antimicrobial Chemotherapy (JAC); Jun1995, Vol. 35 Issue 6, p895-901, 7p
Abstrakt: The suppression of faecal Escherichia coli by quinolones was studied in a randomized cross-over phase I trial with single oral doses of 400 mg rufloxacin or norfloxacin. Both drugs caused > 70% decontamination in a similar number of subjects in the 72 h post-dose period (83% vs 100% respectively), but suppression of E. coli at 168 h was significantly (P < 0.05) higher after rufloxacin (83.3 vs 40%). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index