| Autor: |
Mensa, Josep, Trilla, Antoni, Moreno, Antonio, Vidal, Josep, Espaulella, Joan, Soriano, Eladio, San Miguel, Juan Garcia, Mensa, J, Trilla, A, Moreno, A, Vidal, J, Espaulella, J, Soriano, E, Garcia San Miguel, J |
| Předmět: |
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| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); May1993, Vol. 31 Issue 5, p749-754, 6p |
| Abstrakt: |
This study assessed the efficacy of oral josamycin 1 g bd for five days as treatment for non-severe, community-acquired pneumonia in patients less than 60 years of age who were not at obvious risk of developing respiratory tract infection caused by aerobic Gram-negative bacilli. Of the 84 patients (43 male, 41 female) with a mean age of 33 years who were enrolled during a 14-month period, the clinical outcome was invariabily favourable. All patients became afebrile within three days of starting therapy; the mean duration of fever after initiating treatment was 1·7 days. Therefore, according to the study protocol, josamycin therapy was discontinued on day five. A chest X-ray performed four to six weeks after completing treatment was normal in every case and no relapses were observed during a six-week follow-up period. We conclude that a five-day course of josamycin is effective monotherapy for community-acquired pneumonia in patients without the clinical features of severe infection. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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