| Autor: |
Biglino, Alberto, Forno, Brunella, Pollono, Anna M., Basso, Margherita, Arpinelli, Francesco, Benedetto, Marco, Pugliese, Agostino, Biglino, A, Forno, B, Pollono, A M, Busso, M, Arpinelli, F, Benedetti, M, Pugliese, A |
| Předmět: |
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| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); May1990, Vol. 25 Issue 5, p797-802, 6p |
| Abstrakt: |
The effects of orally administered ofloxacin on functional parameters of cell-mediated immunity were investigated in 15 patients with respiratory or urinary tract infections. Mononuclear leucocytes were obtained before administering the drug, 1 h after the first dose, and five days later. The cells were stimulated with lectins, tetanus toxoid and Newcastle Disease virus in order to assess mitogen- and antigen-induced lymphocyte proliferation and production of γ-interferon, interleulrin-2 and α-interferon. An increase in proliferative response to pokeweed mitogen and a slight but significant decrease in α-interferon production were observed, while other parameters remained unaffected by treatment. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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