Oral acyclovir in herpes zoster.

Autor: McKendrick, M. W., Care, Christine, Burke, Christine, Hickmott, Elaine, McKendrick, G. Donald W., Care, C, Burke, C, Hickmott, E, McKendrick, G D
Zdroj: Journal of Antimicrobial Chemotherapy (JAC); Dec1984, Vol. 14 Issue 6, p661-665, 5p
Abstrakt: Forty-one patients with herpes zoster were treated with acyclovir or placebo at a dosage of 400 mg five times a day by mouth for five days in a double-blind randomized domiciliary study. Acyclovir was shown to reduce the days of new lesion formation within the effected dermatome after day 0 (P = 0.049). No other statistical difference was demonstrated between the two groups although the trends for new lesion formation outside the dermatome, full crusting, involution and diminution of acute pain all favoured acyclovir. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index