| Autor: |
Vught, A. M. J. J. Verweij-van, Namavar, F., Smit, A. M., Sparrius, M., MacLaren, D. M. |
| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); May1982, Vol. 9 Issue 5, p379-385, 7p |
| Abstrakt: |
Mecillinam-resistant spherical mutants of and were tested for virulence. Measurement of LD5O in mice revealed a slight increase in virulence of the mutant strains. The phagocytosis and killing of the mutant strains by human PMN leucocytes were impaired. We conclude that mecillinam-resistant mutants, despite their lower growth-rate, may give problems in patients during mecillinam therapy, especially when the defence mechanisms of the body are impaired. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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