| Autor: |
Tselentis, J., Cordossis, Th., Kosmidis, J., Lambropoulos, S., Melissinos, K. |
| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); Oct1981, Vol. 8 Issue 4, p317-321, 5p |
| Abstrakt: |
The inhibitory activities of azlocillin, mezlocillin, cefotaxime, carbenicillin and ticarcillin were compared using 150 strains of . Azlocillin was the most active antibiotic and mezlocillin the least active. The MICs of azlocillin, mezlocillin, cefotaxime and carbenicillin were measured using ten further strains of producing known β-lactamases. Serum levels of these antibiotics were also measured between 1 and 6 h after a single dose to volunteer patients. Although cefotaxime was stable to all β-lactamases tested the activity of azlocillin was thought to be superior since it combined low MICs with high blood levels and stability to most β-lactamases. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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