| Autor: |
Toner, James P., Brzyski, Robert G., Oehninger, Sergio, Veeck, Lucinda L., Simonetti, Simonetta, Muasher, Suheil J., Toner, J P, Brzyski, R G, Oehninger, S, Veeck, L L, Simonetti, S, Muasher, S J |
| Předmět: |
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| Zdroj: |
Human Reproduction; Feb1991, Vol. 6 Issue 2, p284-289, 6p |
| Abstrakt: |
Three hundred and twenty-seven consecutive in-vitro fertilization (IVF) cycles in which luteal-phase leuprolide had been given were ranked according to the number of pre-ovulatory oocytes obtained (1–5, 6–10, >10). Excess pre-embryos were cryopreserved at the pronuclear stage and later transferred Into monitored natural cycles on the day after ovulation. The results indicate that the retrieval of large numbers of pre-ovulatory oocytes (>10) has a small negative impact on oocyte quality as judged by fertilization rates (4% lower). However, implantation was not impaired compared to lower levels of retrieval in either the original IVF or subsequent cryo–thaw cycles. Overall, despite the small reduction in fertilization rate, the retrieval of many pre ovulatory oocytes has produced a ‘take-home baby rate’ per stimulation cycle of 28.3% when 6–10 pre-ovulatory oocytes were retrieved and 41.5% when >10 were retrieved: even higher rates are anticipated when the remaining cryo preserved pre-embryos are ultimately thawed. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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