The value of menotrophin treatment for unexplained infertility prior to an in-vitro fertilization attempt.

Autor: Simon, Alexander, Avidan, Benjamin, Mordel, Nathan, Lewin, Aby, Samueloff, Arnon, Zajicek, Gershom, Schenker, Joseph G., Laufer, Neri, Simon, A, Avidan, B, Mordel, N, Lewin, A, Samueloff, A, Zajicek, G, Schenker, J G, Laufer, N
Zdroj: Human Reproduction; Feb1991, Vol. 6 Issue 2, p222-226, 5p
Abstrakt: This work was undertaken in order to evaluate retrospectively the relative efficacy of ovulation induction by menotrophins and that of in-vitro fertilization and embryo transfer (IVF–ET) in the treatment of unexplained Infertility. These two treatments were compared between two groups of patients: 87 couples undergoing 446 cycles of ovulation induction by menotrophins (group A) and 72 couples undergo ing 108 cycles of IVF–ET (group B). A total of 30 and 20 pregnancies were achieved in groups A and B for a rate of 34 and 28% per patient, respectively. A similar cumulative pregnancy rate (CPR) was achieved for three cycles of ovulation induction (23%) and one cycle of IVF–ET (22%). The cumulative live birth rate (CLBR) in group A was 22% after three cycles and exceeded that of one IVF–ET cycle (17%). It is concluded that menotrophin treatment in unexplained infertility is highly beneficial and should precede an IVF attempt. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index