| Autor: |
Kotovuori, Pekka, Tontti, Eveliina, Pigott, Rod, Shepherd, Maura, Kiso, Makoto, Hasegawa, Akira, Renkonen, Risto, Nortamo, Pekka, Altieri, Dario C., Gahmberg, Carl G. |
| Zdroj: |
Glycobiology; Mar1993, Vol. 3 Issue 2, p131-136, 6p |
| Abstrakt: |
Leukocyte adhesion involves at least three molecular families of adhesion proteins: the leukocyte integrins CD11/CD18, the intercellular adhesion molecules (ICAMs) and the carbohydrate-binding L-, E- and P-selectins. The intercellular adhesion molecules are well-known ligands for the CD11/CD18 integrins. We now show that E-selectin specifically binds to the sialyl Le carbohydrate epitopes of leukocyte integrins. Thus, the different families of leukocyte adhesion molecules form an integrated adhesion network. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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