| Autor: |
Preston-Martin, Susan, Thomas, Duncan C., White, Stuart C., Cohen, Dierdre |
| Zdroj: |
JNCI: Journal of the National Cancer Institute; 6/16/1988, Vol. 80 Issue 12, p943-949, 7p |
| Abstrakt: |
Findings from this population-based study in Los Angeles County suggest, for the first time, that tumors of the parotid gland are related to prior exposure to diagnostic medical and dental radiography. Responses to interviews with 408 patients with a parotid tumor (269 benign tumors and 139 malignant tumors) were compared to responses of 408 neighborhood controls. Cumulative exposure of the parotid gland from diagnostic radiography was associated with a dose-related increase in risk of malignant tumors ( for trend <.05; relative risk for exposure to ≥50 rad = 3.4; 95% confidence interval = 1.02–11.46). Benign tumors showed a weaker positive association, and exposure before age 20 to a major diagnostic examination (full-mouth or panoramic dental radiography or medical radiography to the head) increased risk (relative risk = 1.8; confidence interval = 1.13–2.91). This study also confirmed the association of malignant tumors with prior radiation treatment to the head or neck; 28% of these tumors are attributable to exposure of the parotid gland from diagnostic and therapeutic radiation. [J Natl Cancer Inst 1988;80:943–949] [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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