Malnutrition, gastroenteritis and trypsinogen concentration in hospitalised Aboriginal children.

Autor: Briars, G.L., Thornton, S.J., Forrest, Y., Ehrlich, J., Shepherd, R.W., Cleghorn, G.J.
Předmět:
Zdroj: Journal of Paediatrics & Child Health; Feb1998, Vol. 34 Issue 1, p69-73, 5p, 4 Charts, 2 Graphs
Abstrakt: Objective: To explore relationships between malnutrition and pancreatic damage in hospitalised aboriginal children.Methods: Immunoreactive trypsinogen (IRT) concentrations were measured in two populations of hospitalised aboriginal children in Australia: 472 children aged 0-3 years, in Alice Springs (Northern Territory); and 187 children aged 0-16 years in Mount Isa (Queensland). Correlation of whole blood IRT with height and weight z-scores, four-site skinfold thickness and upper arm circumference was sought.Results: In Mount Isa, the geometric mean IRT concentration rose with decreasing weight z-score. The IRT concentration was otherwise unrelated to nutritional indices. Sixty percent of the 39 Mount Isa patients with gastroenteritis and 24.5% of the 358 Alice Springs patients with gastroenteritis had an IRT concentration in the upper quartile for their population, compared with 16% for patients with other diagnoses in both populations.Conclusions: A high IRT concentration in patients with low weight z-scores is a confounding effect of gastroenteritis, and may result from subclinical pancreatic disease in gastroenteritis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index