| Autor: |
TAQUET, H., KOMAJDA, M., GRENIER, O., BELAS, F., LANDAULT, C., CARAYON, A., LECHAT, P., GROSGOGEAT, Y., LEGRAND, J. C. |
| Zdroj: |
European Heart Journal; Nov1992, Vol. 13 Issue 11, p1473-1476, 4p |
| Abstrakt: |
To investigate the role of calcitonin gene-related peptide (CGRP) in cardiac failure, a sensitive and specific radioimmu-noassay was developed to study plasma levels of CGRP in 37 normal subjects and 41 patients with heart failure (HF). The mean plasma levels of CGRP were 294·3 pg . ml (SEM: 41·4) in normal subjects and 121·2 pg . ml (SEM: 21·2) in HF patients. The significant decrease observed in HF patients suggests that CGRP is involved in the pathogenesis of heart failure via a direct effect or via modulation of sympathetic nervous activity. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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