Comparative Study of the Clastogenicity of Functionalized and Nonfunctionalized Multiwalled Carbon Nanotubes in Bone Marrow Cells of Swiss-Webster Mice.

Autor:	Patlolla, Anita K., Hussain, Saber M., Schlager, John J., Patlolla, Srikant, Tchounwou, Paul B.
Předmět:	CARBON nanotubes BONE marrow cells LABORATORY mice COMPARATIVE studies BIOCHEMICAL genetics DNA damage CYTOGENETICS BIOCOMPATIBILITY GENETIC toxicology
Zdroj:	Environmental Toxicology; Dec2010, Vol. 25 Issue 6, p608-621, 14p
Abstrakt:	The article presents a comparative study of the clastogenicity of functionalized and nonfunctionalized multiwalled carbon nanotubes (MWCNT) in bone marrow cells of Swiss-Webster mice. The results have distinctly shown a significant increase of cytogenetic damage in the bone marrow cells caused by exposure to MWCNTs using intraperitoneal administration. Moreover, percentages of deviant cells in the bone marrow of a Swiss-webster mice being exposed to MWCNTindicated significant increases as compared to the controls and suggest on careful monitoring with respect to synthesizing biocompatible carbon nanomaterials.
Databáze:	Complementary Index
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