EFFECTS OF CHROMAN DERIVATIVES ON PLATELET AGGREGATION INDUCED BY SOME...

Autor: Aida, Yoko, Kasama, Toshio, Fukuya, Hiroaki, Takeuchi, Naoki, Sugiyama, Kumiko, Tobinaga, Seisho
Předmět:
Zdroj: Clinical & Experimental Pharmacology & Physiology; Nov98, Vol. 25 Issue 11, p939, 6p, 2 Diagrams, 4 Charts
Abstrakt: Examines the effects of synthesized 10 chroman derivatives (CD) derived from khellactone, including preruptorin A and B, on rabbit platelet aggregation. Inhibitory effect of the compounds on platelet-activating factor (PAF)-induced platelet aggregation; Features of compounds with potent PAF antagonist activities; Organic reactions used to synthesize CD-1 TO CD-10 compounds.
Databáze: Complementary Index