Penile rehabilitation therapy with PDE-V inhibitors following radical prostatectomy: proceed with caution.

Autor: Brewer Jr., M. Eric, Kim, Edward D., Brewer, M Eric
Předmět:
Zdroj: Advances in Urology; 2009, Special section p1-4, 4p, 1 Chart
Abstrakt: Penile rehabilitation therapy following radical prostatectomy is a much debated topic. Erectile dysfunction is still a significant contributor to postoperative morbidity following radical prostatectomy, despite meticulous nerve-sparing technique. Secondary smooth muscle changes in the penis have been identified as the underlying causes of penile atrophy, veno-occlusive dysfunction, and fibrosis. Initial observations that intracavernous injection therapies used on a regular basis postoperatively resulted in improvements in the return of spontaneous erectile function led to the development of penile rehabilitation protocols. Chronic dosing of PDE-V inhibitors is now commonly used by urologists after radical prostatectomy. Despite the current enthusiasm of penile rehabilitation therapy, current scientific evidence with clinical trials is still limited. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index