Interferon treatment is not associated with a worsening of psychiatric symptoms in patients with hepatitis C.

Autor: Mulder, Rt, Mulder, Roger T, Ang, Michael, Chapman, B, Ross, Alison, Stevens, Isabel F, Edgar, Christine
Předmět:
Zdroj: Journal of Gastroenterology & Hepatology; Mar2000, Vol. 15 Issue 3, p300-303, 4p, 2 Charts, 1 Graph
Abstrakt: AbstractAim: To study prospectively the psychiatric side effects of interferon-α in patients with hepatitis C. Methods: Sixty-three consecutive patients at a hepatitis clinic were recruited. All were assessed using a psychiatric interview (SCID) and monitored using a self-reporting psychiatric symptom questionnaire (SCL-90). Results: Patients on interferon did not suffer a drop in mood or an increase in anxiety or irritability. The subgroup with past depression also did not suffer an increase in depressive symptoms. No patients attempted suicide. Conclusions: The risk of serious psychiatric symptoms when being treated with interferon-α may not be high. Psychiatric illness or the possibility of psychiatric complications should not be used as a reason to refuse this treatment to patients with hepatitis C. © 2000 Blackwell Science Asia Pty Ltd. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
Externí odkaz: