Application of short tandem repeat of genomic DNA and mitochondrial DNA for identification of mixed-up tissue specimens.

Autor: Sano, Kenji, Takayanagi, Kayoko, Kaneko, Taimei, Liu, Chunyan, Kinoshita, Tomoyuki, Nakamura, Naoshi, Asamura, Hideki, Ito, Makoto, Fukushima, Hirofumi, Hotchi, Masao
Předmět:
Zdroj: Pathology International; Jan2000, Vol. 50 Issue 1, p1-6, 6p
Abstrakt: Deoxyribonucleic acid (DNA) typing methods, short tandem repeat of genomic DNA and mitochondrial DNA with the use of polymerase chain reaction amplification, were applied to formalin-fixed, paraffin-embedded tissues submitted for diagnosis, to identify and sort out mixed-up tissue specimens. These techniques were found to be reliable, reproducible and specific for personal identification, and thus to eliminate the need for further examinations and to prevent unnecessary surgery. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index