| Autor: |
Karukonda, Sree R. K., Flynn, Timothy Corcoran, Boh, Erin E., McBurney, Elizabeth I., Russo, Glenn G., Millikan, Larry E. |
| Předmět: |
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| Zdroj: |
International Journal of Dermatology; Apr2000, Vol. 39 Issue 4, p250, 8p |
| Abstrakt: |
An understanding of basic wound healing physiology is important when discussing the effects of drugs on wound healing. Major advances have occurred within the field of wound healing in the last 20 years. In Part 1 of “The effects of drugs on wound healing”, the phases of wound healing are discussed, the importance of local factors are outlined, and the effects of pharmacologic agents on specific phases of wound healing are presented. Part 2 details specific classes of drugs and their impact on the healing wound. Wound healing involves five phases. These sequential phases are termed: injury, coagulation, inflammation, tissue formation, and tissue remodeling. Each phase lasts a specific length of time and has characteristic cellular elements and extracellular agents, as well as cytokines and growth factors which act as signals, suppressors, and promoters. Figure 1 shows the wound healing cascade and documents the phases. Table 1 details the cellular and extracellular elements involved. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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