| Autor: |
Porter, W. M., O'Gorman-Lalor, O., Lane, R. J. M., Francis, N., Bunker, C. B. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Dermatology; Jun2000, Vol. 25 Issue 4, p277-280, 4p |
| Abstrakt: |
We report a 32-year-old man who presented with a 2-year history of unexplained weight loss and symptoms of Raynaud's phenomenon. Clinical examination and investigations were consistent with a diagnosis of acquired partial lipodystrophy (Barraquer–Simons disease). This patient also exhibited an associated cutaneous vasculitis and peripheral perniotic changes. He had normal renal function and glucose tolerance and no immunological abnormality has been detected in his serum to date. The absence of C3-nephritic factor in the presence of overt lipodystrophy suggests that there may be another factor or immunological mediator responsible for the subcutaneous changes seen in patients with lipodystrophy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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