Autor: |
Steffan, Joan S., Bodai, Laszlo, Pallos, Judit, Poelman, Marnix, McCampbell, Alexander, Apostol, Barbara L., Kazantsev, Alexsey, Schmidt, Emily, Ya-Zhen Zhu, Greenwald, Marilee, Kurokawa, Riki, Housman, David E., Jackson, George R., Marsh, J. Lawrence, Thompson, Leslie M. |
Předmět: |
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Zdroj: |
Nature; 10/18/2001, Vol. 413 Issue 6857, p739, 5p, 4 Color Photographs, 5 Diagrams, 11 Graphs |
Abstrakt: |
Investigates the molecular basis in the development of Huntington's disease. Expansion of a repeated sequence of the amino acid glutamine in abnormal protein huntingtin; Arrest of degeneration through the action of histone deacetylase inhibitors; Potential of including inhibitors in therapy. |
Databáze: |
Complementary Index |
Externí odkaz: |
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