Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation.

Autor: Derand, Renaud, Bulteau-Pignoux, Laurence, Mettey, Yvette, Zegarra-Moran, Olga, Howell, L. Daniel, Randak, Christoph, Galietta, Luis J.V., Cohn, Jonathan A., Norez, Caroline, Romio, Leila, Vierfond, Jean-Michel, Joffre, Michel, Becq, Frederic
Předmět:
Zdroj: American Journal of Physiology: Cell Physiology; Nov2001, Vol. 281 Issue 5, p1657, 10p, 1 Diagram, 1 Chart, 22 Graphs
Abstrakt: Investigates the activation of G551D cystic fibrosis transmembrane conductance regulator (CFTR) channel with 5-butyl-6-hydroxy-10-chlorobenzo[c]quinolizinium chloride (MPB-91). Methods in the conduct of the study; Effect of protein kinase A and C inhibitors; Role of nucleotide binding domain in MPB-91-mediated CFTR activation.
Databáze: Complementary Index