Auger electron spectroscopy for the determination of sex and age related Ca/P ratio at different bone sites.

Autor: Balatsoukas, Ioannis, Kourkoumelis, Nikolaos, Tzaphlidou, Margaret
Předmět:
Zdroj: Journal of Applied Physics; Oct2010, Vol. 108 Issue 7, p074701, 6p, 1 Chart, 2 Graphs
Abstrakt: The Ca/P ratio of normal cortical and trabecular rat bone was measured by Auger electron spectroscopy (AES). Semiquantitative analysis was carried out using ratio techniques to draw conclusions on how age, sex and bone site affect the relative composition of calcium and phosphorus. Results show that Ca/P ratio is not sex dependent; quite the opposite, bone sites exhibit variations in elemental stoichiometry where femoral sections demonstrate higher Ca/P ratio than rear and front tibias. Age-related changes are more distinct for cortical bone in comparison with the trabecular bone. The latter's Ca/P ratio remains unaffected from all the parameters under study. This study confirms that AES is able to successfully quantify bone mineral main elements when certain critical points, related to the experimental conditions, are addressed effectively. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index