The Polycomb group protein EZH2 is unregulated in proliferating, cultured human mantle cell....

Autor: Visser, Hein P.J., Gunster, Marco J., Kluin-Nelemans, Hanneke C., Manders, Erik M.M., Raaphorst, Frank M., Meijer, Chris J.L.M., Willemze, Roel, Otte, Arie P.
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Zdroj: British Journal of Haematology; Mar2001, Vol. 112 Issue 4, p950, 9p, 4 Color Photographs, 1 Diagram, 1 Chart, 1 Graph
Abstrakt: Examines the polycomb group (PcG) proteins involved in the stable transmittance of the repressive state of their gene targets. Identification of PcG protein complexes; Enhancement of EZHZ expression; Effect between EZH2 upregulation and increased proliferation in hematopoietic cells.
Databáze: Complementary Index