Autor: |
Garch, Farid El, Lismond, Ann, Piddock, Laura J. V., Courvalin, Patrice, Tulkens, Paul M., Van Bambeke, Françoise |
Předmět: |
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Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); Oct2010, Vol. 65 Issue 10, p2076-2082, 7p, 1 Chart, 3 Graphs |
Abstrakt: |
Background: Active efflux is a common mechanism of resistance to fluoroquinolones in Streptococcus pneumoniae. Two efflux systems have been described so far in this species: PmrA, a member of the major facilitator superfamily; and the two ABC transporters PatA and PatB. We studied the inducibility of expression of pmrA, patA and patB by using subinhibitory concentrations of fluoroquinolones. [ABSTRACT FROM PUBLISHER] |
Databáze: |
Complementary Index |
Externí odkaz: |
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