| Autor: |
Yuan, Chun-Su, Attele, Anoja S., Dey, Lucy, Lynch, James P., Guan, Xiongfei |
| Zdroj: |
Journal of Clinical Pharmacology; Aug2002, Vol. 42 Issue 8, p899-903, 5p |
| Abstrakt: |
Pain is the majorcomplaint of patients who choose acupunc ture treatment. Transcutaneous electrical acupoint stimulation (TEAS) provides a safe, standardized technique without needle insertion. TEAS can be tested with the cold-pressor test, a simple, reliable, and widely used model in humans for the induction of tonic pain. In this controlled study, the effects of TEAS on cold-pressor-induced pain were evaluated in 20 healthy human subjects. Electrical stimulation electrodes were applied to He-Gu (LI 4) and Nui-Guan (P 6) acupoints. The effects of saline plus no TEAS, 15-minute TEAS alone, 0.05 mg/kg morphine alone, and 15-minute TEAS plus morphine were assessed. Pain score ratings were evaluated at four time points from 30 to 170 seconds during the cold-pressor test. The authors observed analgesic effects in both TEAS-alone and morphine-alone sessions, and pain score rating reductions were statistically significant compared to unstimulated control (both p< 0.01). The degree of TEAS analgesia combined with 0.05 mg/kg morphine was significantly higherthan TEAS alone (p< 0.01). The results support the efficacy of TEAS analgesia and suggest that combination of TEAS with low-dose morphine can achieve better pain control in a variety of clinical settings. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
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