| Autor: |
Koujitani, Takatoshi, Oishi, Hidetoshi, Kubo, Yuji, Maeda, Toshihiro, Sekiya, Keiji, Yasuba, Masashi, Matsuoka, Nobuo, Nishimura, Koichi |
| Zdroj: |
International Journal of Toxicology (Sage); Nov1997, Vol. 16 Issue 6, p611-623, 13p |
| Abstrakt: |
Toxicity studies were conducted to evaluate acute and subchronic oral toxicity and mutagenicity of partially hydrolyzed guar gum (K-13). In an acute toxicity study, mice and rats were treated with K-13 at a dose of 6000 mg/ kg. There were no deaths, so the LD50s were >6000 mg/ kg in both species. In a subchronic toxicity study, K-13 was given to rats as a dietary admixture at concentrations of 0.2. 1.0 and 5.0% for 13 weeks. There were no effects attributable to K-13 in any examinations. K-13 proved to have no mutagenic potential in a reverse mutation test using bacteria. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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