Subclinical activation of lupus nephritis by recombinant human growth hormone.

Autor: Yap, Hui-Kim, Loke, Kah-Yin, Murugasu, Belinda, Lee, Bee-Wah
Předmět:
Zdroj: Pediatric Nephrology; 1998, Vol. 12 Issue 2, p133-135, 3p
Abstrakt: The effect of growth hormone (GH) on subclinical disease activity in a 15-year-old boy with previously quiescent lupus nephritis and chronic renal failure is described. Institution of supraphysiological doses of GH resulted in a rise in erythrocyte sedimentation rate, decrease in serum complement, rise in anti-DNA antibody titers, and increase in T-cell activation markers, all of which improved following cessation of GH treatment. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index