Low Sensitivity of the Leukocyte Esterase Test (LET) in Detecting Chlamydia trachomatis Infections in Asymptomatic Men Entering a County Jail.

Autor: Ratelle, Sylvie, Nguyen, Meeta S., Tang, Yuren, Whelan, Michael, Etkind, Paul, Lincoln, Thomas, Dumas, William
Zdroj: Journal of Correctional Health Care; Jan2004, Vol. 10 Issue 2, p217-226, 10p
Abstrakt: Objectives: To determine the test performance characteristics of the leukocyte esterase test (LET) in detecting Chlamydia trachomatis (CT) infections in asymptomatic men entering a county jail. Methods: First-void urine of 2,176 men was simultaneously tested for urethral inflammation by the LET and for CT by the ligase chain reaction (LCR). Results: Using the LCR as reference standard, the sensitivity, specificity, and positive and negative predictive values of the LET with confidence intervals were 6.1% (2.7, 12.7), 98.5% (97.9, 99.0), 18.4% (8.3, 34.9), and 95.1% (94.0, 95.9), respectively. Conclusion: The LET lacks sensitivity in detecting asymptomatic chlamydial infection among men entering a correctional facility. Alternatives should be sought as cost-saving strategies. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index