| Autor: |
McKenzie, F. Ellis, Wong, Roger C., Bossert, William H. |
| Zdroj: |
Simulation; Oct1999, Vol. 73 Issue 4, p213-217, 5p |
| Abstrakt: |
We extend our basic discrete-event model of Plasmodium falciparum malaria to encom pass circumstances in which multiple pheno typic variants of the parasite circulate within interacting human and mosquito populations, and we compare a version in which variants behave independently to one in which they in teract through shared host immune responses. Relative to the standard hypothesis of statisti cal independence, frequencies of mixed-pheno type infection in humans were as expected in the independent-immunity version and much less than expected in the cross-immunity ver sion ; in both versions, however, such frequen cies in mosquitoes were much greater than expected. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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