Effect of Oral Vitamin E on Oxy-Free Radical Status in Acute Myocardial Infarction.

Autor: Chandra, Mahesh, Gupta, Vivek, Rathi, Anil Kumar, Vaish, Arvind Kumar, Srimal, Rikhab Chand, Pandey, Vikas Chand, Ghatak, Ashim, Sircar, Amulya Ranjan, Bhardwaj, Rajpal Singh, Singhal, Shyam Sunder
Zdroj: Asian Cardiovascular & Thoracic Annals; 1995, Vol. 3 Issue 3/4, p117-122, 6p
Abstrakt: The present work was conducted to study the status of oxidative stress (oxy-free radicals) in 24 patients with acute myocardial infarction and 12 matched healthy control patients and furthermore evaluate the effect of oral vitamin E on altered oxy-free radicals in these patients. The parameters assessed for oxy-free radical status were superoxide anion and malonyldialdehyde. These were found to be increased during acute myocardial infarction and this increment had a normalizing trend with the passage of time. It was found that the administration of vitamin E accelerated the normalizing trend of both superoxide anion and malonyldialdehyde. Thus, vitamin E has an antioxidant effect in acute myocardial infarction. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index