| Autor: |
Perez-Cordova, Miriam G., Jaime, Saul, Guajardo, Herminio, Colom1,2, Luis V. |
| Předmět: |
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| Zdroj: |
BMC Neuroscience; 2010 Supplement 1, Vol. 11, p1-1, 1p |
| Abstrakt: |
The article discusses a study that looks at the role of Medial Septal/Diagonal Band (MS/DB) GABAergic neurons in hippocampal theta rhythm amplitude modulation. The study used antibody Gamma amino butyric acid Transporter 1 (GAT-1) conjugated to saporin (SAP, 3μL at 325ng/μL) to inject in the MS/DB of adults Sprague Dawley rats to destroy GABAergic neurons. The results reveal that observed reduction of theta rhythm is associated with 75 percent loss of MS/DB GABAergic neurons. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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