A Study of Paclitaxel, Carboplatin, and Bortezomib in the Treatment of Metastatic Malignant Melanoma.

Autor: Croghan, Gary A., Suman, Vera J., Maples, William J., Albertini, Mark, Linette, Gerald, Flaherty, Lawrence, Eckardt, John, Ma, Cynthia, Markovic, Svetomir N., Erlichman, Charles
Předmět:
Zdroj: Cancer (0008543X); 7/15/2010, Vol. 116 Issue 14, p3463-3468, 6p, 2 Charts, 1 Graph
Abstrakt: The article offers information on a study which examined the antitumor activity of bortezomib combined with paclitaxel and carboplatin in patients with metastatic melanoma who had received at least one before chemotherapy for metastatic disease. The dosage and duration of treatment with bortezomib, paclitaxel and carboplatin is detailed. Main outcome measure was tumor response rate (TRR). A discussion on the research findings is detailed.
Databáze: Complementary Index