| Autor: |
Deghmane, Ala-Eddine, du Chatelet, Isabelle Parent, Szatanik, Marek, Hong, Eva, Ruckly, Corinne, Giorgini, Dario, Lévy-Bruhl, Daniel, Alonso, Jean-Michel, Taha, Muhamed-Kheir |
| Předmět: |
|
| Zdroj: |
Journal of Infectious Diseases; 7/15/2010, Vol. 202 Issue 2, p247-250, 4p, 2 Graphs |
| Abstrakt: |
In France, there have been variations in the incidence of invasive meningococcal infection due to serogroup C isolates. Infection peaks were observed in 1992 and 2003 that involved isolates of phenotypes C:2a:P1.5,2 and/or C:2a:P1.5, which belong to the sequence type 11 (ST-11) clonal complex. We report an emergence of isolates belonging to the ST-11 clonal complex since 2003. These isolates displayed a new phenotype, C:2a:P1.7,1, caused infections that occurred as clusters, and were associated with increased infection severity and high virulence in mice. These isolates may be responsible for a peak in the incidence of serogroup C meningococcal infection in France, for which there is no routine vaccination to date. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
