Bifunctional compounds eliciting anti-inflammatory and anti-cholinesterase activity as potential treatment of nerve and blister chemical agents poisoning.

Autor: Amitai, Gabi, Adani, Rachel, Fishbein, Eliezer, Meshulam, Haim, Laish, ldo, Dachir, Shlomit
Předmět:
Zdroj: Journal of Applied Toxicology; Jan/Feb2006, Vol. 26 Issue 1, p81-87, 7p, 5 Graphs
Abstrakt: The article presents a study about the therapeutic potential of bifunctional compounds, including pyridostigmine (PYR), ibuprofen (IBU) and diclofenac (DICLO). The study found that the compounds, which elicit non-steroidal anti-inflammatory drug (NSAID) and anti-cholinesterase (anti-ChE) activity, are effective in treating nerve and blister chemical agents poisoning. The article details who the study was conducted and the methods used by researchers.
Databáze: Complementary Index