Association of SF-36 With Coronary Artery Disease Risk Factors and Mortality: A PreCIS Study.

Autor: Zhang, Jian-Ping, Pozuelo, Leo, Brennan, Danielle M., Hoar, Brian, Hoogwerf, Byron J.
Zdroj: Preventive Cardiology; Summer2010, Vol. 13 Issue 3, p122-129, 8p, 4 Charts, 2 Graphs
Abstrakt: This study examined the relationships among health-related quality of life and risk factors of coronary artery disease (CAD) and all-cause mortality in high-risk cardiac patients seen in a cardiology prevention clinic. At baseline, 1785 patients (age, 53.4±13.4 years; 58.8% men) had a medical history, physical examination, and laboratory tests. They completed the Medical Outcomes Study Short Form–36-Item Health Survey (SF-36). Analyses were conducted on associations of 2 SF-36 domain scores (overall physical health [OPH] and overall mental health [OMH]) with CAD biomarkers and all-cause mortality. Lower OPH scores were associated with CAD risk factors including smoking; history of hypertension, diabetes, and peripheral artery disease; the metabolic syndrome; and other novel CAD biomarkers. Lower OMH scores showed similar but weaker associations with CAD risk factors. OPH significantly predicted 5-year mortality in multivariable survival analysis. SF-36, especially OPH, was associated with many risk factors of CAD and significantly predicted mortality. Prev Cardiol. 2010;13:122–129.©2009 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index