| Autor: |
Tsyv'yan, P., Bashmakova, N., Artem'eva, O., Panacheva, N., Orekhova, V., Protsenko, Yu. |
| Zdroj: |
Human Physiology; May2004, Vol. 30 Issue 3, p319-323, 5p |
| Abstrakt: |
Fetuses of 24 women with normal pregnancies and 14 women with fetal intrauterine growth retardation (IUGR) were tested for shape and movement of the inner borders of the left ventricle (LV) by means of echocardiography. The LV contour was divided into 12 segments. The coefficient of variation (CV) of the movements of individual wall segments was calculated to assess regional nonuniformity of contractions of the LV wall. The ratio between the long and short LV axes was lower in the IUGR group (1.12 ± 0.12) than in the control group (1.75 ± 0.16). Nonuniformity of contractions was higher in the IUGR group (CV = 37.8 ± 17.6%) than in the control group (CV = 21.1 ± 9.9%, P < 0.01). The ratio of the early wave to the atrial wave of transmitral flow (E/A ratio) was lower in the IUGR group (0.69 ± 0.08) than in the control group (0.80 ± 0.08). A negative correlation between the CV and the global ejection fraction of the LV was observed in the fetuses of both groups. In addition, a negative correlation was demonstrated for the E/A ratio and the systolic-to-diastolic flow ratio (S/D ratio) in the umbilical artery. Changes in the shape, nonuniformity of contractions, and diastolic function of the heart in IUGR fetuses are considered to be an adaptation to increased afterload as a result of an elevated resistance of placental vessels. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink