| Autor: |
Zoppi, Massimo, Beneforti, Elisabetta |
| Zdroj: |
Current Pain & Headache Reports; Apr1999, Vol. 3 Issue 2, p121-129, 9p |
| Abstrakt: |
Joint pain may result from traumas or repeated microtraumas, as in sports injuries. Pain in osteoarthritis starts before any objective finding. It has been demonstrated that in the first stages of this disease, pain is due to intraosseous venous engorgement for the earlier thickening of the cortical bone under the articular cartilage. The mechanisms of inflammatory pain are more complex because all the joint tissues are involved, and a network of cytokines are released from nociceptive terminal endings (neuropeptides), macrophages, synovial cells, and other related sites. All these substances intermingle and are responsible together for all the signs of inflammation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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