Evaluation of various methods of intravenous contrast enhancement for thoraco-abdominal spiral CT scanning in trauma patients.

Autor: Killeen, K. L., Markert, D. J., Sherbourne, C. D., Shanmuganathan, K., Mirvis, S. E., Murray, S. P.
Zdroj: Emergency Radiology; May2000, Vol. 7 Issue 2, p85-88, 4p
Abstrakt: The purpose of this study was to determine the optimal contrast concentration, volume, and injection rate for helical CT imaging of trauma patients requiring evaluation of the chest, abdomen, and pelvis. Two hundred forty patients were randomized into six different regimen groups for administration of iohexol nonionic intravenous contrast medium, each regimen containing 36 g iodine, with various injection rates, volumes, and concentrations of intravenous contrast enhancement. Parenchymal and vascular enhancement was objectively measured by obtaining pre- and post-contrast attenuation values of the thoracic and abdominal aorta, liver, and spleen, as well as post-contrast attenuation values of vascular enhancement of the portal vein and iliac artery. The contrast-enhanced images were subjectively reviewed by four radiologists blinded to the contrast administration techniques and objective evaluation results. It was found that while our ability to evaluate the abdominal organs was essentially equivalent with all six contrast administration regimens, our ability to evaluate the thoracic aorta was significantly better using 150 ml iohexol (Omnipaque 240) at 3 ml/s than with the other methods. Therefore, we recommend the use of 150 ml iohexol (Omnipaque 240) at 3 ml/s for combined chest and abdominal studies in patients with blunt trauma. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index