Synthesis of novel bioconjugates of α-tocopherol with lupane triterpenoids.

Autor: Spivak, A. Yu., Mufazzalova, R. R., Shakurova, E. R., Odinokov, V. N., Dzhemilev, U. M.
Předmět:
Zdroj: Russian Chemical Bulletin; Jan2010, Vol. 59 Issue 1, p241-250, 10p, 1 Diagram, 3 Charts
Abstrakt: The first representatives of gA-tocopherol bioconjugates with lupane triterpenoids were synthesized using amino acid residues and dipeptides as linkers between the antioxidant molecule and the terpenoid C(28) atom. The synthetic combination of natural compounds was carried out by the reaction of lupane acid chlorides (betulonic and betulinic acid chlorides) with amino acid and dipeptide derivatives of gA-tocopherol. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index