| Autor: |
Gilsbach, Ralf, Schneider, Johanna, Lother, Achim, Schickinger, Stefanie, Leemhuis, Jost, Hein, Lutz |
| Předmět: |
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| Zdroj: |
Cardiovascular Research; Jun2010, Vol. 86 Issue 3, p432-442, 11p, 2 Charts, 6 Graphs |
| Abstrakt: |
Aims: α2-Adrenoceptors modulate cardiovascular function by vasoconstriction or dilatation, by central inhibition of sympathetic activity, or by feedback inhibition of norepinephrine release from sympathetic neurons. Despite detailed knowledge about subtype-specific functions of α2-receptors, the relative contributions of sympathetic vs. non-sympathetic receptors involved in these cardiovascular effects have not been identified. The aim of this study was to define the physiological and pharmacological role of α2A-adrenoceptors in adrenergic vs. non-adrenergic cells at baseline and during sympathetic stress. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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