| Autor: |
Ciancaglini, Pietro, Yadav, Manisha C., Simão, Ana Maria Sper, Narisawa, Sonoko, Pizauro, João Martins, Farquharson, Colin, Hoylaerts, Marc F., Millán, José Luis |
| Zdroj: |
Journal of Bone & Mineral Research; Apr2010, Vol. 25 Issue 4, p716-723, 8p, 4 Black and White Photographs, 1 Diagram, 3 Graphs |
| Abstrakt: |
The article discusses the result of a study which analyzed phosphosubstrate catalysis by osteoblast-derived matrix vesicles (MV). It was found that adenosine triphosphate (ATP) is the main substrate hydrolyzed by the wild-type MV and that tissue-nonspecific alkaline phosphatase (TNAP) had the most significant effect on the hydrolysis of substrates. The study concludes that TNAP is an enzyme responsible for hydrolyzing ATP and extracellular inorganic phosphatase. |
| Databáze: |
Complementary Index |
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