GC/MS Analysis of the Competitive Alkylation of 2-Methylcyclohexanone: A New Experiment for Undergraduate Students.

Autor:	PADIAS, ANNE, BARON, JAMES
Zdroj:	Chemical Educator; 1998, Vol. 3 Issue 3, p1-11, 11p
Abstrakt:	In this organic chemistry laboratory experiment, students perform two different alkylations of α-methylcyclohexanone. Conditions have been established that allow the students to achieve efficient anion formation using lithium diisopropylamide in tetrahydrofuran. First, the enolate is alkylated with either allyl bromide or benzyl bromide and the product analyzed by GC/MS. Subsequently, a competitive alkylation is performed using both electrophiles and the reaction mixture analyzed by GC/MS. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Full text from SpringerLink