High Throughput Analysis and Purification in Support of Automated Parallel Synthesis.

Autor: Weller, Harold, Young, Marian, Michalczyk, Stephen, Reitnauer, Gary, Cooley, Robert, Rahn, Peter, Loyd, Dana, Fiore, Dario, Fischman, Steven
Zdroj: Molecular Diversity; Apr1997, Vol. 3 Issue 1, p61-70, 10p
Abstrakt: Rapid reverse-phase analytical and preparative HPLC methods havebeen developed for application to parallel synthesis libraries.Gradient methods, short columns, and high flow rates allowanalysis of over 300 compounds per day on a single system, orpurification of up to 200 compounds per day on a singlepreparative system. Hardware and software modifications allowcontinuous unattended use for maximum efficiency and throughput. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index