Molybdenum supply of very low-birth-weight premature infants during the first months of life.

Autor: Sievers, Erika, Schleyerbach, Urte, Arpe, Thomas, Garbe-Schönberg, Dieter, Schaub, Jürgen
Zdroj: Biological Trace Element Research; May2001, Vol. 80 Issue 2, p97-106, 10p
Abstrakt: This explorative study was performed to assess basic data on the Mo metabolism of premature infants. Premature ( n=18, gestational age ≤32 wk, birth weight ≤1500 g) and healthy formula-fed term infants ( n=14) were nourished and corrected for gestational age, identically. Plasma was collected at 3, 16, and 52 wk and 72 h balances were performed at 3 wk of age. In the premature infants, these investigations were preceded by two balance studies and an initial plasma collection. Increased Mo intake and low relative urinary excretion resulted in a retention of 4.4 (0.99–7.77) µg Mo/kg initially in premature infants (median, range). Parallel plasma concentrations were 5.5 (2.5–7.3) µg Mo/L, declining to 2.36 (0.73–3.87) µg Mo/L at 4 wk. Term infants rendered 1.49 (0.29–1.7) µg Mo/L ( p<0.05), with no significant differences later. It was concluded that the supplementation of formulas for premature infants with Mo should be recinded until there is evidence for its necessity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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