Pain model and fuzzy logic patient-controlled analgesia in shock-wave lithotripsy.

Autor:	Shieh, J., Chang, L., Wang, M., Wang, Y., Yang, Y., Sun, W., Shieh, J S, Chang, L W, Wang, M S, Sun, W Z, Wang, Y P, Yang, Y P
Předmět:	KIDNEY stones ALFENTANIL ALGORITHMS ANALGESICS CLINICAL trials COMPARATIVE studies DRUG administration LITHOTRIPSY LOGIC RESEARCH methodology MEDICAL cooperation NARCOTICS PATIENT-controlled analgesia RESEARCH EVALUATION research THERAPEUTICS
Zdroj:	Medical & Biological Engineering & Computing; Jan2002, Vol. 40 Issue 1, p128-136, 9p
Abstrakt:	Pain control in conscious patients was investigated using a push-button, demand-driven supply of drugs. A fuzzy logic patient-controlled analgesia (PCA) algorithm was compared with a conventional algorithm, for alfentanil administration in extracorporeal shock-wave lithotripsy. The conventional PCA algorithm used an initial dose of 0.25mg, a fixed infusion rate of 60 mg h(-1) and a fixed bolus size of 0.2 mg with a 1 min lockout. The fuzzy logic PCA algorithm used an initial dose of 0.25 mg, a changeable infusion rate and a bolus size of 0.1 or 0.05 mg. The infusion rate was adjusted according to a look-up table that accepted the button-pressing history over the last three lockout intervals. The look-up table was designed using fuzzy logic. The bolus size was adjusted according to the button-pressing history over the past two lockout intervals. Twelve patients were treated using conventional PCA, and thirteen were treated with PCA + fuzzy logic control (FLC). PCA + FLC patients consumed 45% less drug. Also, PCA + FLC patients had a mean delivery/demand ratio of 82%, compared with 60% in conventional PCA. When the pain intensity scale was analysed, PCA + FLC patients had acceptable pain intensity at 62%, compared with 44% in conventional PCA. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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