Bone Metastases from Secondary Glioblastoma Multiforme: A Case Report.

Autor: Cervio, Andrés, Piedimonte, Fabián, Salaberry, Juan, Alcorta, Santiago, Salvat, Jorge, Diez, Blanca, Sevlever, Gustavo
Zdroj: Journal of Neuro-Oncology; Apr2001, Vol. 52 Issue 2, p141-148, 8p
Abstrakt: Extraneural metastases of glioblastoma multiforme (GBM) are a relatively rare occurrence which usually manifest after de novo GBM. We report a case of a patient with an oligodendroastrocytoma who developed over a period of 12 years malignant progression to glioblastoma followed by multiple cytologically confirmed bone metastases. No 1p deletions were detected in the original tumour. GBM cells disclosed the EGFr(+) and p53(−) immunophenotype more characteristic of a primary GBM. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index