Controversies in new antibiotic therapy for ambulatory patients.

Autor: Sundararajan, V., Rubenstein, Edward B., Rolston, Kenneth V. I., Elting, Linda S., Rubenstein, E B, Rolston, K V, Elting, L S
Zdroj: Supportive Care in Cancer; Sep1997, Vol. 5 Issue 5, p358-364, 7p
Abstrakt: The care of the febrile neutropenic patient has undergone a shift in the last 10 years with the realization that neutropenic patients presenting with fever do not constitute a homogeneous group. Strategies of risk assessment have allowed the testing of novel therapies including outpatient treatment with oral and intravenous antibiotics, either in combination regimens or as monotherapy; the addition of growth factors to hasten the return of the absolute neutrophil count; and the possibility of self-initiation of antibiotics by cancer patients when they develop fever. The clinical trials data regarding these new approaches will be reviewed, and areas requiring further research will be discussed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index