Preparation and Fungitoxicity of Some Trichloro-, Tribromo-, Tetrachloro-, and Tetrabromo-8-Quinolinols.

Autor: Gershon, Herman, Clarke, Donald D., Gershon, Muriel
Zdroj: Chemical Monthly / Monatshefte für Chemie; Sep2001, Vol. 132 Issue 9, p1075-1080, 6p
Abstrakt: 3,5,6-, 3,5,7-, 4,5,7-, and 5,6,7-trichloro- and -tribromo-8-quinolinols as well as 3,5,6,7-tetrachloro- and -tetrabromo-8-quinolinols were prepared and tested against six fungi ( Aspergillus niger, Aspergillus oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes) in Sabouraud dextrose broth. The compounds strongly inhibit five fungi but not M. cirinelloides. They are less active than the related dichloro-8-quinolinols which is attributed to steric hindrance. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index