| Autor: |
Lafaut, B. A., De Backer, E., Kohno, T., De Laey, J.-J., Meire, F. M. |
| Zdroj: |
Graefe's Archive of Clinical & Experimental Ophthalmology; Feb2000, Vol. 238 Issue 2, p158-162, 5p |
| Abstrakt: |
· Purpose: To report the indocyanine green angiographic findings in patients with a fundus dystrophy characterized by subretinal deposits, macular atrophic or neovascular degeneration and peripheral chorioretinal atrophy which is most likely Sorsby’s fundus dystrophy. · Methods: A series of 11 clinically affected patients and 4 asymptomatic carriers, belonging to one autosomal dominant pedigree were examined with stereoscopic funduscopy, fluorescein and indocyanine green angiography. · Results: Subretinal deposits were found in 20 eyes of 10 patients. These deposits stained slightly on indocyanine green angio-graphy, causing a reticular pattern. Two eyes had a disciform lesion and 3 geographic atrophy in the macula. A peripheral disciform lesion was found in 1 eye. Indocyanine green angiography identified peripapillary choroidal neovascularization in 2 eyes. Peripheral chorioretinal atrophy was found in 8 eyes of 4 patients, associated with peripheral plaques that could only be identified by indocyanine green angiography in 6 eyes of 3 patients. · Conclusion: Indocyanine green angiography in Sorsby’s fundus dystrophy may indicate the presence of homogeneously staining, well-demarcated peripheral areas of hyperfluorescence associated with chorioretinal atrophy. These plaques correspond in our opinion to choroidal neovascularization which is otherwise unsuspected. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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